Abstract
Background: According to WHO estimates, more than 2 billion people worldwide have been infected with Hepatitis B Virus, and hepatitis B has seriously harmed human health.Objective: This study aims to understand the current status of hepatitis B infection in college students, to explore the performance patterns and composition ratios of hepatitis B virus serum markers, and to propose corresponding preventive measures for the diagnosis and treatment of hepatitis B infection in colleges and universities. Methods: In this paper, 681 people were selected from the four grades of a university by random sampling method. A total of 2724 college students were used to detect two pairs of serum hepatitis B by ELISA. At the same time, the corresponding questionnaires were conducted. Results: A total of 1947 hepatitis B virus serum markers were detected in 2724 serum samples, and the total positive rate was 71.5%. The hepatitis B virus serum markers formed a total of 7 serological patterns. The positive rates of HBsAg, HBeAg and anti-HBcAg were 1.32%, the positive rates of HBsAg, anti-HBc and anti-HBe were 0.44%, and the positive rates of anti-HBs and HBsAg were 0.44% and 0.55%, respectively, and the positive rate of total infection group was 2.75%. At the same time, the factors that affect the total positive rate of hepatitis B include: whether the vaccine is vaccinated, whether the birth place is rural or urban; the factors affecting the single positive rate of serum anti-HBs markers also include gender. Conclusion: The HBsAg positive rate of hepatitis B virus serological markers in college students is lower than the national average. The hepatitis B vaccine for college students is the most effective preventive method for active immunization of hepatitis B. Colleges and universities should strengthen health education interventions, isolate patients early, and strive for full coverage of hepatitis B vaccine.

Keywords
College Students, Serological Markers, Serological Testing, HBV

Cite this paper
Li-fa Xu, Chang-hao Hou, Xiao-huan Lu, Analysis of Detection Results of Hepatitis B Virus Serological Markers in College Students , SCIREA Journal of Clinical Medicine. Volume 4, Issue 1, February 2019 | PP. 1-10.

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